According to me there is Yes, there are some risks with using ceftriaxone injections, like with any medicine. Some people may get mild side effects such as pain or swelling where the injection was given, rash, or diarrhea. In rare cases, it can cause serious allergic reactions, liver or kidney problems, or blood issues. It should be used carefully in people with allergies to antibiotics or with certain health problems. Always follow the doctor’s advice and let them know if you notice any bad reaction after the injection.