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Muscle twitches are derived from tiny involuntary muscle contractions. These contractions occur in response to confused signals sent from the brain and spinal cord to strands of nerve fibers within your muscles. Once a group of muscles receive the message — muscles respond only in small groups — they begin to contract. Calf muscle twitching: the low back and calf muscle connection the nerves that branch off of your spine in your low back connect to the muscles in the legs. Drug-induced tremor is a simple nervous system and muscle response to certain medicines. Drugs that can cause tremor include the following: cancer medicines such as thalidomide and cytarabine; seizure medicines such as valproic acid (depakote) and sodium valproate (depakene) asthma medicines such as theophylline and albuterol. Glucocorticoid-induced muscle atrophy prevention by exercise in fast-twitch fibers. J appl physiol (1985) 1990 sep; 69 (3):1058–1062. Seene t, viru a. The catabolic effect of glucocorticoids on different types of skeletal muscle fibres and its dependence upon muscle activity and interaction with anabolic steroids. The achy joints, nausea, vomiting, trembling and water retention caused by steroids may have an adverse effect on the physical activity necessary for training muscles. Steroids have been known to cause osteoporosis; a weakened skeletal system makes for a weakened musculoskeletal system. While i have had this kind of twitching in the past, this is a marked increase. But it's good to know *why* the muscle twitching is an issue – it doesn't sound like mine is so serious. I drink plenty of water, and i eat a banana every morning – hopefully that's enough potassium to at least keep me from becoming deficient. Thanks for your help. Myoclonic twitches or jerks usually are caused by sudden muscle contractions (tightening), called positive myoclonus, or by muscle relaxation, called negative myoclonus. Myoclonic jerks may occur alone or in sequence, in a pattern of movement or without pattern. They may occur infrequently or many times per minute. In this video we demonstrate the technique for treating a severe trapezius muscle spasm with steroid and bupivacaine injections. I have added 10 pounds since stopping my first cycle. But i recently have experienced muscle cramps or spasms. Not while doing a crunch for example, but go to lay on the floor (after doing 2 sets of 25 already) and it feels like an abdomen muscle tightens up real hard (i lay in the fetal position and breath heavy for a few minutes). In some instances, medications ranging from antidepressants and anti-anxiety medications to stimulants and steroids can cause muscle twitching. He says that the onset of symptoms coincided with the tapering of corticosteroids, which was initially at a dose of 60 mg/kg/day during 15 days, 26 jan 2009. Right now for the past two days my tricep has been twitching like crazy i mean i violent twitching i can see it it shakes my arm. 5 gallons of water a day i supplement with potassium on top of the potassium i get from food sources i make sure i don't go over via tracking on my fitness pal. "prednisone is the drug that caused my husbands problems in his muscles, so would methotrexate alone be enough to stop his twitching calf muscles?" answered by dr. Ronald krauser: no: methotrexate has no benefit for muscle twitching

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