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Most TEAEs reported with tapentadol PR are of mild or moderate price of tapentadol tapentadol mechanism tapentadol schedule class palexia medication palexia sr intensity .
In a long-term safety trial (1 year, KF5503/24), the incidence of constipation for subjects tapentadol on tapentadol PR was markedly lower than for oxycodone CR .
The safety profile following exposure of up to 1 year was not tapentadol qualitatively different to that following shorter exposure .
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